Towards a Conceptual Framework for Innate Immunity

TL;DR

This paper reviews innate immunity principles and proposes a conceptual framework to incorporate these into artificial immune system models, aiming to advance bio-inspired computational approaches.

Contribution

It introduces a meta-framework for modeling innate immunity, addressing the gap in artificial immune systems inspired by innate rather than adaptive immunity.

Findings

Identifies key biological principles of innate immunity

Proposes a conceptual framework for artificial models

Lays groundwork for future bio-inspired immune system design

Abstract

Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity. This paper reviews the biological principles and properties of innate immunity and, adopting a conceptual framework, asks how these can be incorporated into artificial models. The aim is to outline a meta-framework for models of innate immunity.