Improving the recombination estimation method of Padhukasahasram et al 2006

TL;DR

This paper enhances the recombination estimation method of Padhukasahasram et al. 2006 by incorporating additional statistics and fixed segregating sites simulations, resulting in improved accuracy.

Contribution

It introduces a modified approach with new summary statistics and simulation strategies, improving estimation accuracy over the original method.

Findings

Improved recombination estimation accuracy.

Inclusion of additional informative summary statistics.

Availability of a C++ program for implementation.

Abstract

The accuracy of the recombination estimation method of Padhukasahasram et al. 2006 can be improved by including additional informative summary statistics in the rejection scheme and by simulating datasets under a fixed segregating sites model. A C++ program that outputs these summary statistics is freely available from my website.