Smoothing proximal gradient method for general structured sparse regression
Xi Chen, Qihang Lin, Seyoung Kim, Jaime G. Carbonell, Eric P. Xing

TL;DR
This paper introduces a smoothing proximal gradient method for efficiently solving high-dimensional structured sparse regression problems with complex penalties, outperforming traditional methods in speed and scalability.
Contribution
The paper proposes a novel smoothing proximal gradient approach that handles nonseparable, nonsmooth structured sparsity penalties with improved convergence and scalability.
Findings
The method achieves faster convergence rates than standard first-order and subgradient methods.
It is significantly more scalable than interior-point methods.
Demonstrated effectiveness on simulation and genetic data sets.
Abstract
We study the problem of estimating high-dimensional regression models regularized by a structured sparsity-inducing penalty that encodes prior structural information on either the input or output variables. We consider two widely adopted types of penalties of this kind as motivating examples: (1) the general overlapping-group-lasso penalty, generalized from the group-lasso penalty; and (2) the graph-guided-fused-lasso penalty, generalized from the fused-lasso penalty. For both types of penalties, due to their nonseparability and nonsmoothness, developing an efficient optimization method remains a challenging problem. In this paper we propose a general optimization approach, the smoothing proximal gradient (SPG) method, which can solve structured sparse regression problems with any smooth convex loss under a wide spectrum of structured sparsity-inducing penalties. Our approach combines a…
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