Radiation stability of biocompatibile magnetic fluid

TL;DR

This study investigates how electron irradiation affects the stability of biocompatible magnetic fluids, revealing that PEG surfactant provides significant protection against radiation-induced magnetization loss.

Contribution

It demonstrates that adding PEG as a second surfactant enhances the radiation stability of biocompatible magnetic fluids compared to single-surfactant formulations.

Findings

PEG reduces magnetization loss after irradiation

PEG decreases sedimentation of magnetic particles

Biocompatible magnetic fluids with PEG are more radiation-resistant

Abstract

The radiation stability of biocompatibile magnetic fluid used in nanomedicine after electron irradiation was studied. Two types of the water-based magnetic fluids were prepared. The first one was based on the magnetite nanoparticles stabilized by one surfactant natrium oleate. The second one was biocompatibile magnetic fluid stabilized with two surfactants, natrium oleate as a first surfactant and Poly(ethylene glycol) (PEG) as a second surfactant. The magnetization measurements showed that electron irradiation up to 1000Gy caused 50% reduction of saturation magnetization in the case of the first sample with only one surfactant while in the case of the second biocompatibile magnetic fluid, only 25% reduction of saturation magnetization was observed. In the first magnetic fluid the radiation caused the higher sedimentation of the magnetic particles than in the second case, when magnetic particles are covered also with PEG. The obtained results show that PEG behave as a protective element.