Monocyte and T-lymphocyte trans-endothelial migration in relation to cardiovascular disease: some alternative boundary conditions in a model recently proposed by Little et al. (PLoS Comput Biol 2009 5(10) e1000539)

TL;DR

This paper proposes a slight modification to a mathematical model of immune cell migration related to cardiovascular disease, providing alternative parameter estimates without altering the original conclusions.

Contribution

It introduces a modified boundary condition in an existing model, offering new parameter estimates while maintaining the original model's results.

Findings

Alternative parameter estimates derived

Original model results and conclusions unchanged

Provides a refined understanding of cell migration dynamics

Abstract

We consider a slight modification to the monocyte and T-lymphocyte boundary conditions of Little et al. (PLoS Comput Biol 2009 5(10) e1000539) and derive alternative parameter estimates. No changes to the results and conclusions of the paper of Little et al. (PLoS Comput Biol 2009 5(10) e1000539) are implied.