Nano-Biotechnology: Structure and Dynamics of Nanoscale Biosystems

TL;DR

This paper reviews the structure and dynamics of nanoscale biosystems, emphasizing molecular simulations and applications like nanomachines and drug delivery devices.

Contribution

It provides a comprehensive overview of natural nanomachines, simulation studies, and the development of nanodevices such as nanosyringes for medical use.

Findings

Molecular simulations elucidate nanomachine dynamics.

Carbon nanotubes mimic biological channels.

Nanosystems enable needle-free drug delivery.

Abstract

Nanoscale biosystems are widely used in numerous medical applications. The approaches for structure and function of the nanomachines that are available in the cell (natural nanomachines) are discussed. Molecular simulation studies have been extensively used to study the dynamics of many nanomachines including ribosome. Carbon Nanotubes (CNTs) serve as prototypes for biological channels such as Aquaporins (AQPs). Recently, extensive investigations have been performed on the transport of biological nanosystems through CNTs. The results are utilized as a guide in building a nanomachinary such as nanosyringe for a needle free drug delivery.