# GenRank: an R/Bioconductor package for prioritization of candidate genes

## TL;DR

GenRank is an R package that helps scientists prioritize important genes from large lists by combining multiple sources of evidence.

## Contribution

The novel contribution is an extensible R/Bioconductor package for gene prioritization using convergent evidence from multiple layers.

## Key findings

- GenRank provides methods for candidate gene prioritization based on convergent evidence.
- The package is implemented in R and available in the Bioconductor repository.

## Abstract

Modern high-throughput studies often yield long lists of genes, of which a fraction are of high relevance to the phenotype of interest. To prioritize the candidate genes of complex genetic traits, our R/Bioconductor package GenRank provides methods that are based on convergent evidence obtained from multiple independent evidence layers. The package facilitates an extensible framework that allows a further addition of novel methods for candidate gene prioritization.

The methods are implemented in R and available as a package in Bioconductor repository (http://bioconductor.org/packages/GenRank/).

chakra.kanduri@gmail.com