Structure and stability of helices in square-well homopolymers

TL;DR

This study investigates the conditions under which square-well homopolymers form stable helical structures, revealing how interaction parameters and chain length influence helix stability and morphology.

Contribution

It provides a detailed analysis of how well width and chain stiffness affect helix formation and stability in square-well homopolymers, using advanced simulation techniques.

Findings

Helix radius decreases with increasing well width.

Helices are stable only within a specific chain length window.

Polymer stiffness determines the uniqueness of the low-temperature structure.

Abstract

Recently, it has been demonstrated [Magee et al., Phys. Rev. Lett. 96, 207802 (2006)] that isolated, square-well homopolymers can spontaneously break chiral symmetry and freeze into helical structures at sufficiently low temperatures. This behavior is interesting because the square-well homopolymer is itself achiral. In this work, we use event-driven molecular dynamics, combined with an optimized parallel tempering scheme, to study this polymer model over a wide range of parameters. We examine the conditions where the helix structure is stable and determine how the interaction parameters of the polymer govern the details of the helix structure. The width of the square well (proportional to lambda) is found to control the radius of the helix, which decreases with increasing well width until the polymer forms a coiled sphere for sufficiently large wells. The helices are found to be stable for only a window of molecular weights. If the polymer is too short, the helix will not form. If the polymer is too long, the helix is no longer the minimum energy structure, and other folded structures will form. The size of this window is governed by the chain stiffness, which in this model is a function of the ratio of the monomer size to the bond length. Outside this window, the polymer still freezes into a locked structure at low temperature, however, unless the chain is sufficiently stiff, this structure will not be unique and is similar to a glassy state.