Modeling of zonal electrophoresis in plane channel of complex shape

TL;DR

This paper presents a mathematical model of zonal electrophoresis in complex-shaped plane channels, highlighting how stagnation regions, electromigration, and convection influence the distribution of admixtures, aiding in understanding experimental results.

Contribution

The study introduces a computational approach to model electrophoresis in complex channels, accounting for stagnation zones, electromigration, and convection effects, which were previously not well understood.

Findings

Stagnation regions can form in S-type rectangular channels.

Electromigration and convection significantly affect admixture zone shape.

The model explains complex experimental electrophoresis results.

Abstract

The zonal electrophoresis in the channels of complex forms is considered mathematically with the use of computations. We show that for plane S-type rectangular channels stagnation regions can appear that cause the strong variations of the spatial distribution of an admixture. Besides, the shape of an admixture zone is strongly influenced by the effects of electromigration and by a convective mixing. Taking into account the zone spreading caused by electromigration, the influence of vertex points of cannel walls, and convection would explain the results of electrophoretic experiments, which are difficult to understand otherwise.