Defocus test and defocus correction in full-field optical coherence tomography

TL;DR

This paper demonstrates an experimental method to detect and correct defocus caused by refractive index mismatch in full-field optical coherence tomography, improving image sharpness in biological tissues.

Contribution

It introduces a metric-based approach to compensate for index-induced defocus in full-field OCT, enhancing imaging quality of biological samples.

Findings

Successful correction of defocus in biological tissue imaging

Recovery of sharp images in depth after correction

Validation of the method through experimental evidence

Abstract

We report experimental evidence and correction of defocus in full-field OCT of biological samples due to mismatch of the refractive index of biological tissues and water. Via a metric based on the image quality, we demonstrate that we are able to compensate this index-induced defocus and to recover a sharp image in depth.