Theoretical and numerical investigations on shapes of planar lipid monolayer domains

TL;DR

This paper combines theoretical derivations and numerical simulations to analyze the equilibrium shapes of planar lipid monolayer domains, revealing both known and novel shapes that await experimental validation.

Contribution

It introduces a shape equation derived from energy minimization and a relaxation method for numerical solutions, advancing understanding of lipid monolayer domain geometries.

Findings

Theoretical and numerical results align with experimental observations.

New domain shapes are predicted, not yet observed experimentally.

The shape equation effectively describes boundary curves at equilibrium.

Abstract

Shapes of planar lipid monolayer domains at the air-water interface are theoretically and numerically investigated by minimizing the formation energy of the domains which consist of the surface energy, line tension energy, and dipole electrostatic energy. The shape equation which describes boundary curves of the domains at equilibrium state is derived from the first order variation of the formation energy. A relaxation method is proposed to find the numerical solutions of the shape equation. The theoretical and numerical results are in good agreement with previous experimental observation. Some new shapes not observed in previous experiments are also obtained, which awaits experimental confirmation in the future.