Membrane tension lowering induced by protein activity
M. D. El Alaoui Faris, D. Lacoste, J. Pecreaux, J-F. Joanny, J. Prost, and P. Bassereau
TL;DR
This study measures how protein activity, specifically bacteriorhodopsin pumps, affects membrane tension by analyzing vesicle fluctuations, revealing that pump activation lowers membrane tension.
Contribution
It provides experimental evidence linking protein activity to membrane tension modulation through fluctuation spectrum analysis.
Findings
Activation of bacteriorhodopsin increases low wavevector fluctuations.
Protein activity lowers the effective tension of the membrane.
Fluctuation spectrum analysis can detect tension changes due to protein activity.
Abstract
We present measurements of the fluctuation spectrum of giant vesicles containing bacteriorhodopsin (BR) pumps using video-microscopy. When the pumps are activated, we observe a significant increase of the fluctuations in the low wavevector region, which we interpret as due to a lowering of the effective tension of the membrane.
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Taxonomy
TopicsPhotoreceptor and optogenetics research · Lipid Membrane Structure and Behavior · Spectroscopy and Quantum Chemical Studies