Prediction of genomic properties and classification of life by protein length distributions

TL;DR

This paper demonstrates that protein length distributions encode evolutionary information, enabling the prediction of genome properties and classification of life into three domains based on their structural patterns.

Contribution

It introduces a novel approach linking protein length distributions to genome size, non-coding DNA content, and phylogenetic classification, revealing intrinsic relationships and structural order.

Findings

Genome size and non-coding DNA can be predicted from protein length distributions.

Protein length distributions exhibit correlations and quasi-periodicity.

Life can be classified into three domains based on distribution structures.

Abstract

Much evolutionary information is stored in the fluctuations of protein length distributions. The genome size and non-coding DNA content can be calculated based only on the protein length distributions. So there is intrinsic relationship between the coding DNA size and non-coding DNA size. According to the correlations and quasi-periodicity of protein length distributions, we can classify life into three domains. Strong evidences are found to support the order in the structures of protein length distributions.