Phenomenological modeling of DNA overstretching
Ray W. Ogden (Department of Mathematics, University of Glasgow,, Scotland, UK), Giuseppe Saccomandi (Dipartimento di Ingegneria Industriale,, Universita' degli Studi di Perugia, Italy), Ivonne Sgura (Dipartimento di, Matematica, Universita' del Salento, Lecce, Italy)
TL;DR
This paper introduces a phenomenological nonlinear elasticity model to accurately describe the overstretching behavior observed in DNA's force-extension curves, providing a unified formula for data fitting.
Contribution
It develops a novel 3D nonlinear elasticity model using multiple reference configurations to effectively model DNA overstretching.
Findings
The model fits experimental force-extension data well.
A single formula captures the overstretching phenomenon.
The approach advances understanding of DNA mechanics.
Abstract
A phenomenological model based on the three-dimensional theory of nonlinear elasticity is developed to describe the phenomenon of overstretching in the force-extension curve for dsDNA. By using the concept of a material with multiple reference configurations a single formula is obtained to fit the force-extension curve.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsForce Microscopy Techniques and Applications · Nanopore and Nanochannel Transport Studies · Elasticity and Material Modeling