A mean-field version of the Nicodemi-Prisco SSB model for X-chromosome inactivation
G. Gaeta
TL;DR
This paper develops a mean-field approximation of the Nicodemi-Prisco model to better understand the spontaneous symmetry-breaking mechanism underlying X-chromosome inactivation in mammals.
Contribution
It introduces a mean-field version of the existing model, providing a simplified analytical framework for studying X-chromosome inactivation.
Findings
Mean-field model captures key features of symmetry breaking
Simplifies analysis of X-chromosome inactivation dynamics
Provides insights into the stability of inactive X-chromosome state
Abstract
Nicodemi and Prisco recently proposed a model for X-chromosome inactivation in mammals, explaining this phenomenon in terms of a spontaneous symmetry-breaking mechanism [{\it Phys. Rev. Lett.} 99 (2007), 108104]. Here we provide a mean-field version of their model.
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