1953: An unrecognized summit in human genetic linkage analysis
E.A. Thompson
TL;DR
This paper reviews the historical development of human genetic linkage analysis methods, highlighting the significance of the 1953 paper by C. A. B. Smith and its impact on the field.
Contribution
It provides a comprehensive discussion of the methodological advancements in human genetic linkage analysis from 1953 onwards, emphasizing previously unrecognized contributions.
Findings
Historical overview of linkage analysis methods
Recognition of 1953 Smith paper's importance
Discussion of subsequent methodological developments
Abstract
This paper summarizes and discusses the methodological research in human genetic linkage analysis, leading up to and following from the paper of C. A. B. Smith presented as a Royal Statistical Society discussion paper in 1953. This paper was given as the Fisher XXVII Memorial Lecture, in Cambridge, December 4, 2006.
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