Step-up simultaneous tests for identifying active effects in orthogonal saturated designs
Samuel S. Wu, Weizhen Wang

TL;DR
This paper introduces two step-up testing procedures for identifying active effects in orthogonal saturated designs, controlling the experimentwise error rate under effect sparsity assumptions.
Contribution
The paper proposes novel step-up simultaneous testing methods that effectively identify active effects while controlling error rates in orthogonal saturated designs.
Findings
Procedures control the experimentwise error rate at the specified alpha level
Methods are applicable under the assumption of effect sparsity
The procedures are proven to control error rates strongly
Abstract
A sequence of null hypotheses regarding the number of negligible effects (zero effects) in orthogonal saturated designs is formulated. Two step-up simultaneous testing procedures are proposed to identify active effects (nonzero effects) under the commonly used assumption of effect sparsity. It is shown that each procedure controls the experimentwise error rate at a given level in the strong sense.
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Taxonomy
TopicsOptimal Experimental Design Methods · Advanced Statistical Methods and Models · Statistical Methods in Clinical Trials
