Fitting analysis provides further evidence for eradication of hiv/aids infection under combined liposome drug delivery treatment
E. E. Gabev (1), Evgeni B. Gabev (2), E. E. Gabev Jr. (1), M. V., Bogoeva (3) ((1) Institute of Experimental Pathology, Parasitology,, Bulgarian Academy of Sciences (2) Medical University, Sofia, Bulgaria, (3), Institute of Zoology, Bulgarian Academy of Sciences, Sofia, Bulgaria)

TL;DR
The paper presents a linear regression analysis of viral load data suggesting that a combined liposome drug delivery treatment could lead to complete HIV eradication, challenging current treatment limitations.
Contribution
It introduces a novel linear regression approach to demonstrate potential HIV eradication under a new combined liposome drug delivery method.
Findings
Viral load follows a linear decay trend under the proposed treatment.
Linear regression indicates potential for complete HIV eradication.
Results suggest a feasible pathway to eradicate HIV within a reasonable timeframe.
Abstract
It is now evident that the commonly accepted strategy for treatment of HIV/AIDS by highly active antiretroviral therapy (HAART) will not lead to eradication of HIV in a reasonable time. This is straightforward from the typical exponential viral load decay upon treatment revealing initial considerable but incomplete reduction of plasma HIV RNA with subsequent low level HIV persistence even in patients on effective antiretroviral therapy. Here we show that the viral load follows a simple zero trend linear regression line under different treatment approach recently proposed by us. This unambiguously indicates a whole body HIV eradication in reasonable time.
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Taxonomy
TopicsHIV Research and Treatment · Reproductive tract infections research · HIV, Drug Use, Sexual Risk
